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          DSPE-PEG-OH的合成與結(jié)構(gòu)表征
          發(fā)布時間:2025-07-04     作者:kx   分享到:

          文獻:粘膜粘附脂質(zhì)體遞送系統(tǒng)協(xié)同*炎和*氧化作用增強對干眼病的*

          鏈接:https://www.sciencedirect.com/science/article/abs/pii/S0168365924001391

          作者:黃 可欣,榮 國 ,浩源 羅阿 ,劉厚 勤,東辰  ,鄧濤  ,李嘉欣  ,焦 河 阿,徐 祝平,曼麗 啊,秦 禾

          節(jié)選:

          CsA/Cro PBA 唇膜的制備及表征

          DSPE-PEG-PBA 的合成路線如圖 S1所示。通過;磻,4-羧基-3-氟苯基硼酸成功連接到 DSPE-PEG-NH 2 上[50]。DSPE-PEG-PBA 的化學結(jié)構(gòu)通過1 H NMR表征。如圖 S2所示,在 DSPE-PEG-PBA 的譜圖中,9.5 ppm 處 4-羧基-3-氟苯基硼酸的羧基峰消失,而在 7.5~8.0 ppm 處觀察到 PBA 上苯環(huán)和酰胺鍵的特征峰

          Preparation and characterization of the CsA/Cro PBA lip

          The synthetic route of DSPE-PEG-PBA is shown in Fig. S1. Through acylation reaction, 4-Carboxy-3-fluoro-phenylboronic acid was successfully linked to DSPE-PEG-NH2 [50]. The chemical structure of DSPE-PEG-PBA was characterized by 1H NMR. As shown in Figs. S2, in the spectrum of DSPE-PEG-PBA, the carboxyl peak of 4-carboxy-3-fluoro-phenylboronic acid at 9.5 ppm disappeared, while the characteristic peaks of the benzene ring on PBA and the amide bond were observed at 7.5–8.0 ppm

          DSPE-PEG-OH

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